Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists

J Med Chem. 1991 Sep;34(9):2919-22. doi: 10.1021/jm00113a035.

Authors

N B Mantlo¹, P K Chakravarty, D L Ondeyka, P K Siegl, R S Chang, V J Lotti, K A Faust, T B Chen, T W Schorn, C S Sweet, et al.

Affiliation

¹ Exploratory Chemistry Merck Sharp and Dohme Research Laboratories, Rahway, New Jersey 07065.

PMID: 1895308
DOI: 10.1021/jm00113a035

No abstract available

MeSH terms

Administration, Oral
Angiotensin Receptor Antagonists*
Animals
Antihypertensive Agents
Imidazoles / pharmacology
Purines / pharmacology*
Rats
Tetrazoles / pharmacology

Substances

Angiotensin Receptor Antagonists
Antihypertensive Agents
Imidazoles
Purines
Tetrazoles
1H-imidazo(4,5-b)pyridine
L 158809